OSRC Research

Computer simulation models:

Computer Modelling and Simulation refers to the process of constructing and manipulating computer-based mathematical, graphical or algorithmic representations of real-life systems or phenomena, for the purpose of conducting computer-based simulations to study, predict or optimise the behaviour of the system(s) / phenomena under consideration. The complexities of modern biomedicine are rapidly increasing. Thus, modeling and simulation have become increasingly important as a strategy to understand and predict the trajectory of pathophysiology, disease genesis, and disease spread in support of clinical and policy decisions.

Aims:

  • Estimate model parameters and model boundary conditions through both quantitative and qualitative approaches
  • Develop mathematical models and computer simulation to study patient journeys across entire care pathways, from management of health in the home to acute care and specialist services
  • Conduct rigorous testing and validation studies of the resulting models and simulations to demonstrate their usability and fitness for purpose
  • Maximising impact through translation from research prototypes to market-ready/user-ready products
  • Develop innovative modelling techniques and simulation algorithms with the ultimate aim of supporting patient-specific mission rehearsal, training and procedure navigation

Computer simulation models have many important applications:

  • Test the effects of interventions by using blood investigations, patients reported outcome measures and daily monitoring charts combined.
  • Test the drugs in the randomised trials.
  • Assessing surgical outcome.
  • Assessing the effect of recovery and enabling planning of early discharge.
  • Detect patterns of disease deterioration.

Assessment of pre-operative optimisation bundle in patients with inflammatory bowel disease

Objective assessment of the optimization outcomes is one of the most challenging research questions. This project is based on literature review, construction, testing and validation of computer simulation models to assess the outcome.

These models will combine blood investigations, daily monitoring charts and digitally collected patient-reported outcome measures.

Contact us if you have some knowledge/experience about the subject and wish to get involved.

Investigation of the efficiency of post-operative recovery in elderly patients admitted to the hospital

Our elderly patients’ population is growing. The recovery of those patients take time and it is difficult to assess. Many healthcare, economic and legal decisions are built on assessment of recovery.

The project will create models to combine blood investigations, daily monitoring charts, digitally collected patient-reported outcome measures and clinical assessments.

Contact us if you have some knowledge/experience about the subject and wish to get involved

 

Where are standing now and where we are heading to?

We are the stage of building the background knowledge, establish partnerships and raise funds to researchers and research equipment.