Publications by OpenSourceResearch Collaboration

 OpenSourceResearch Collaboration & ReplicaAnalytics

An evaluation of the replicability of analyses using synthetic health data

Scientific Reports

DOI:https://doi.org/10.1016/j.patter.2024.100946

The study considered two different types of generative models and also looked at the impact of data amplification.

Some interesting observations include that: when analyzed properly, data amplification has marginal value for improving the replicability of statistical analyses, replicability is maximized when ten synthetic datasets are generated and the resultant models are combined (as one does with multiple imputation), and that replicability does vary quite a bit with the type of generative model.

 OpenSourceResearch Collaboration & ReplicaAnalytics

An evaluation of synthetic data augmentation for mitigating covariate bias in health data

Cell

DOI:https://doi.org/10.1016/j.patter.2024.100946

Important publication about synthetic data augmentation

The study compares the efficacy of bias-mitigating approaches in real-world health #data

Performance is evaluated based on predictive accuracy, parameter precision, and fairness

 OpenSourceResearch Collaboration 

Peak performance in surgery: how machine learning can improve surgical performance

impact-surgery 

DOI: https://doi.org/10.62463/surgery.15

Surgical research is associated with specific methodological and practical challenges related to the assessment of complex interventions and variation of clinical equipoise. Biases can, to some degree, be overcome by randomisation, blinding, and intervention standardisation, although randomised trials can be costly and time-consuming. 

This poses a unique opportunity for innovation in surgical research design and evaluation  trials and their assessment. 

 OpenSourceResearch Collaboration 

Burnout among surgeons before and during the SARS-CoV-2 pandemic: an international survey

BMC Psychology 

BMC Psychol 12, 48 (2024). https://doi.org/10.1186/s40359-023-01517-4

Members of OSRC participated in this important contribution. The article concludes that There was a significant burnout among trainees. 

 OpenSourceResearch Collaboration 

Systematic Review of the Effect of Non-steroidal Anti-Inflammatory Drugs on the Exacerbation of Inflammatory Bowel Disease

Turk J Colorectal Dis 2023;33(4):92-102

Online publication

This article is part of investigator initiated research by members of OSRC. The aim of this systematic review is to investigate evidence on the role NSAIDs play in the exacerbation of IBD

 OpenSourceResearch Collaboration 

We need to rethink how to improve surgical research

Danish Medical Journal

Online publication

This article was written to encourage discussion of surgical research. Claims that surgical research are “comic operas” are not unsubstantiated as this article shows.

 OpenSourceResearch Collaboration 

How Computer Vision and Big Data Analytics are Revolutionizing Surgery

Medicioggi

Online publication

This study was part of OpenSourceResearch Collaboration project
which aimed to explore The role of AI in assessment of surgical video films

 OpenSourceResearch Collaboration 

Preoperative assessment of blood supply and its role in predicting anastomotic leak

Surgery

2023 doi:

10.1016/j.surg.2023.04.001

Online ahead of print

This study was part of OpenSourceResearch Collaboration project
which aimed to explore The role of AI in radiology

 OpenSourceResearch Collaboration 

Watchful waiting after radiological guided drainage of intra-abdominal abscess in patients with Crohn’s disease might be associated with increased rates of stoma construction

Crohn’s & Colitis 360

2023 doi:

https://doi.org/10.1093/crocol/otad038

Online ahead of print

This study was part of OpenSourceResearch Collaboration project
which aimed to explore The need for AI research in IBD

 OpenSourceResearch Collaboration 

Risk of anorectal cancer in patients with Crohn’s disease and perianal fistula: a nationwide Danish cohort study

Colorectal disease

2023 Apr 21.  doi: 10.1111/codi.16581. 

Online ahead of print.

This study was part of OpenSourceResearch Collaboration project
which aimed to explore register data as part of big data mining

 OpenSourceResearch Collaboration 

Algorithms to anonymize structured medical and healthcare data: A systematic review

Frontiers in Bioinformatics

Front. Bioinform., 22 December 2022

This study was part of OpenSourceResearch Collaboration project
which aimed to improve data management and sharing.

 OpenSourceResearch Collaboration 

Outcomes of emergency surgical interventions in right-sided colonic cancer: nationwide population-based study based on Danish Colorectal Cancer Group register

BJS Open

Volume 7, Issue 1, February 2023, zrac153

This study was part of OpenSourceResearch Collaboration project
which aimed to explore register data as part of big data mining

 OpenSourceResearch Collaboration 

Comparison of Microbiological Profile of Drained Intra-Abdominal Abscess in Patients with Crohn’s Disease and Colonic Diverticulitis

Turkish Journal of Colorectal diseases

Turk J Colorectal Dis 2022;32(4):252-257

This study was part of OpenSourceResearch Collaboration project
which aimed to explore collaboration in management of IBD optimize it.

Members of OpenSourceResearch Collaboration participated in ECCO research

ECCO Topical Review: Roadmap to optimal peri-operative care in IBD

J Crohns Colitis

DOI: 10.1093/ecco-jcc/jjac129

This study was part of OpenSourceResearch Collaboration project
which aimed to explore collaboration in management of IBD optimize it.

 OpenSourceResearch Collaboration 

Inflammatory response in patients with Crohn’s Disease Compared to Ulcerative Colitis: secondary results of a prospective pilot study

Crohns Colitis 360

DOI:doi.org/10.1093/crocol/otac047

This study was part of OpenSourceResearch Collaboration project
which aimed to explore collaboration in management of IBD optimize it.

OpenSourceResearch Collaboration

The use of datasets collected by surgical collaborating groups

British Journal of Surgery 2021 (ahead of print).

https://doi.org/10.1093/bjsopen/zrab075

This study was part of OpenSourceResearch Collaboration project
which aimed to explore collaboration in research and how to optimize it.

OpenSourceResearch Collaboration

Current status and future perspectives of collaboration in surgical research: A scoping review of the evidence

Surgery 2021 (ahead of print).

https://doi.org/10.1016/j.surg.2021.04.031

This study was part of  OpenSourceResearch Collaboration project
which aimed to improve collaboration in research.

OpenSourceResearch Collaboration

Types, limitations, and possible alternatives of peer review based on the literature with the surgeons’ opinions via Twitter: a narrative review.

Science editing journal 2021 (ahead of print).

This study was part of  OpenSourceResearch Collaboration project
which aimed to explore collaboration in research and how to optimize it.

OpenSourceResearch Collaboration

Postoperative complications and waiting time for surgical intervention after radiologically guided drainage of intra-abdominal abscess in patients with Crohn’s disease

British Journal of Surgery 2021 (ahead of print).

https://doi.org/10.1093/bjsopen/zrab075

This study was part of  OpenSourceResearch Collaboration project
which aimed to investigate pre-operative optimization of patients with Crohn’s disease.

OpenSourceResearch Collaboration

Patient-reported outcome measures in colorectal surgery: Construction of core measures using open source research method

Surgical Innovation 2021 (ahead of print).

https://doi.org/10.1177/1553350621998871

This study was part of  OpenSourceResearch Collaboration project
which aimed to explore optimization of pre-and postoperative course.

OpenSourceResearch Collaboration

Extended right sided colon resection does not reduce the risk of colon cancer local-regional recurrence: Nation-wide population-based study from Danish Colorectal Cancer Group Database

Dis Colon Rectum

DOI: 10.1097/DCR.0000000000002358

This study was part of  OpenSourceResearch Collaboration project
which aimed to explore local-regional recurrence in colon cancer.

Linda Tutty, Alaa El-Hussuna.

The power and potential of using social media to connect patients and health professionals

How social media can be used to empower patients, promote self management, and co-develop a “real world” core set of patient reported outcome measures for those undergoing colorectal surgery

BMJ Opinion, 2021

This article was part of OpenSourceResearch Collaboration project which aimed to explore the optimization of pre-and post operative course.

OpenSourceResearch Collaboration

Biological treatment and the risk of unfavorable postoperative outcome in patients with inflammatory bowel disease: An open source conducted review of the current literature and future perspectives by an expert panel.

Crohn’s & Colitis 360. 2019

https://doi.org/10.1093/crocol/otz021

This study was part of  OpenSourceResearch Collaboration project
which aimed to explore pre-operative optimization of patients with IBD.

Alaa El-Hussuna, Sameh H Emile, Steven D Wexner.

Comment on “Novel approaches to surgical trials and the assessment of new surgical technologies”: The OpenSourceResearch collaboration to conduct research using online tools and social media.

British Journal of Surgery 2020

https://doi.org/10.1093/bjs/znaa061

This article was part of  OpenSourceResearch Collaboration project
which aimed to explore collaboration in research and how to optimize it.

Alaa El-Hussuna, Gaetano Gallo

Research as Part of Daily Clinical Life: Challenging But Possible

J Surg Res Prac. 2021;2(2):1-4.

http://dx.doi.org/10.46889/JSRP.2021.2203

This article was part of  OpenSourceResearch Collaboration project
which aimed to explore collaboration in research and how to optimize it.

OpenSourceResearch Collaboration 

Information Technologies to Support Research: Challenges and Action Plan.

Editorial by Alaa El-Hussuna

EC Gastroenterology and Digestive System 8.4 (2021).

This article was part of  OpenSourceResearch Collaboration project
which aimed to explore collaboration in research and how to optimize it.

 

Ali Yalcinkaya, Alaa El-Hussuna.

#OpenSourceResearch: A novel medical research technique/style in terms of accessibility and way of work.

Colorectal dis. 2020

https://doi.org/10.1111/codi.15392

This article was part of  OpenSourceResearch Collaboration project
which aimed to explore collaboration in research and how to optimize it.

Alaa El-Hussuna, Jeppe Lang

We need to rethink how to improve surgical research

Danish medical journal

Dan Med J 2022;69(6):A205119

This article was part of  OpenSourceResearch Collaboration project
which aimed to explore collaboration in research and how to optimize it.

OpenSourceResearch in collaboration with EuroPower group

Association between use of enhanced recovery after surgery protocols and postoperative complications in colorectal surgery in Europe

J Clin Anesth.

2022 Apr 8;80:110752.

This article explores the optimization of surgical patients. Read more about OSRC optimization projects here

Khaled El Emam, Lucy Mosquera, Xi Fang & Alaa El-Hussuna

Utility Metrics for Evaluating Synthetic Health Data Generation Methods: A Validation Study

JMIR Medical Informatics 2022

This article was part of  OpenSourceResearch Collaboration project
which aimed to explore data de-identification